Curcumin has shown antitumor effects in breast cancer. HER2 positive. It can induce cell death in breast cancer cells by inducing changes in the cell membrane potential.
Cancer stem cells are one of the main causes of cancer recurrence after treatment. Cancer stem cells are responsible for resistance to chemotherapy after a period of treatment, therefore, research to develop approaches that allow the destruction of cancer stem cells is of much importance. Curcumin has shown its ability to kill cancer stem cells, in addition to increasing the effectiveness of chemotherapy in the treatment of breast cancer.